Research References

The RAPC System has been used with a positive reinforcement-based operant paradigm that has alternating performance and learning components during each experiment session, with different auditory stimuli signaling which component is currently in effect. This unique positive reinforcement based paradigm allows the researcher to evaluate learning versus rote performance on a within-subject and within-behavioral test session basis (Brooks et al. 2000).

Neurobiology of Learning and Memory 74:241-258 (2000)

Repeated acquisition and performance chamber for mice: a paradigm for assessment of spatial learning and memory. Read more»

Brooks AI, Cory-Slechta DA, Murg SL, Federoff HJ.

PNAS Vol. 97, No. 24, 13378-13383 (2000)

Gene-experience interaction alters the cholinergic septohippocampal pathway of mice Read more»

Andrew I. Brooks, Deborah A. Cory-Slechta, and Howard J. Federoff

PNAS Vol. 99, No. 9, 6216-6221 (2002)

Functional correction of established central nervous system deficits in an animal model of lysosomal storage disease with feline immunodeficiency virus-based vectors. Read more»

Brooks AI, Stein CS, Hughes SM, Heth J, McCray PM Jr, Sauter SL, Johnston JC, Cory-Slechta DA, Federoff HJ, Davidson BL.

J Physiology 543P S290 (2002)

Deciphering the molecular mechanisms underlying memory and learning: a functional genomics approach to studying the ageing and diseased brain Read more»

E.R. Detrait, C. Cox, D.A. Cory-Slechta, R. Bijlani, Y. Cheng, D.A. Pearce, M. Ogihara, E.K. Richfield and A.I. Brooks